The Senate on Monday confirmed Lori Chavez-DeRemer 67-32 to lead the Labor Department.
More than a dozen Democrats joined Republicans in backing the former House lawmaker, who garnered support from some labor union leaders and business groups.
Chavez-DeRemer is set to take charge at Labor as the Trump administration seeks major cutbacks at the agency and across the government as part of a deregulatory sweep the White House is betting will juice the economy.
Her path to confirmation was rockier than initially anticipated. She was one of only a few House Republicans to sponsor a union-backed suite of labor law reforms known as the “PRO Act” — a stance that several conservatives, like Sen. Rand Paul (R-Ky.), questioned during her confirmation hearing.