Centrus and Palantir partner on US uranium enrichment

By Francisco "A.J." Camacho | 03/13/2026 06:39 AM EDT

The use of artificial intelligence to generate real-time data on nuclear centrifuges aims to speed up fuel development for advanced reactors.

Peter Thiel

Peter Thiel, co-founder of Palantir, speaks during the Bitcoin 2022 Conference at the Miami Beach Convention Center on April 7, 2022, in Miami. Marco Bello/Getty Images

Centrus Energy, the only American-owned company currently enriching uranium, announced Thursday it was partnering with AI software company Palantir to smooth its deployment of infrastructure needed to power the next generation of nuclear power plants.

The deal has already identified nearly $300 million in “potential cost savings and efficiencies” since late January, according to Centrus. It comes days after Centrus announced it is pursuing a joint venture with California-based reactor developer Oklo to co-locate uranium enrichment and deconversion services in Ohio.

“We faced a hard truth: Our paper-based processes were too slow. Our data couldn’t keep up,” Patrick Brown, senior vice president of Centrus’ field operations, said at a Palantir marketing event. “So we needed to think differently. We needed a partner.”

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The Centrus partnership comes amid somewhat choppy waters for Palantir. President Donald Trump is trying to wean the Department of Defense off of Anthropic’s Claude AI model, which is integrated into Palantir’s products. That could threaten Palantir’s extensive contracts with the federal government, which total roughly $2 billion since 2008.

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